PSME2 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： PSME2 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： PSME2 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00005721-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human PSME2 protein.
- Immunogen:
- PSME2 (AAH04368.1, 1 a.a. ~ 239 a.a) full-length human protein.
- Sequence:
- MAKPCGVRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDIPIPDPPPKDDEMETDKQEKKEVPKCGFLPGNEKVLSLLALVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFSERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKIVNPKGEEKPSMY
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- PSME2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSME2 expression in mouse spleen.
- Protocol Download
- Western Blot (Cell lysate)
- PSME2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PSME2 expression in HepG2.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of PSME2 expression in transfected 293T cell line (H00005721-T01) by PSME2 MaxPab polyclonal antibody.
Lane 1: PSME2 transfected lysate(27.40 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 5721
- GeneBank Accession#:
- BC004368.1
- Protein Accession#:
- AAH04368.1
- Gene Name:
- PSME2
- Gene Alias:
- PA28B,PA28beta,REGbeta
- Gene Description:
- proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
- Omim ID:
- 602161
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13. [provided by RefSeq
- Other Designations:
- 11S regulator complex beta subunit,MCP activator, 31-kD subunit,activator of multicatalytic protease subunit 2,cell migration-inducing protein 22,proteasome activator 28-beta,proteasome activator hPA28 subunit beta,proteasome activator subunit 2
- Gene Pathway
- Related Disease