MYC (phospho S62) monoclonal antibody, clone 33A12E10-抗体-抗体-生物在线
亚诺法生技股份有限公司(Abnova)
MYC (phospho S62) monoclonal antibody, clone 33A12E10

MYC (phospho S62) monoclonal antibody, clone 33A12E10

商家询价

产品名称: MYC (phospho S62) monoclonal antibody, clone 33A12E10

英文名称: MYC (phospho S62) monoclonal antibody, clone 33A12E10

产品编号: MAB6763

产品价格: null

产品产地: 台湾

品牌商标: Abnova

更新时间: null

使用范围:

亚诺法生技股份有限公司(Abnova)
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  • 所在区域 : 台湾
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  • 邮箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic phosphopeptide of MYC.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding S62 of human MYC.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b, kappa
  • Storage Buffer:
  • In antiserum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 2.
  • CIP2A inhibits PP2A in human malignancies.
    Junttila MR, Puustinen P, Niemela M, Ahola R, Arnold H, Bottzauw T, Ala-aho R, Nielsen C, Ivaska J, Taya Y, Lu SL, Lin S, Chan EK, Wang XJ, Grenman R, Kast J, Kallunki T, Sears R, Kahari VM, Westermarck J.Cell. 2007 Jul 13;130(1):51-62.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot from crude cell extracts of AGS (gastric adenocarcinoma) cells with MYC (phospho S62) monoclonal antibody, clone 33A12E10 (Cat # MAB6763).
    Lane 1 : Scrambled siRNA was introduced into the cells as a negative control.
    Lane 2 : Negative control siRNA from Qiagen was transfected.
    Lane 3 : siRNA for MYC was transfected.
    The data was provided by A. Khanna and Dr. J. Westermark of University of Tampere.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4609
  • Gene Name:
  • MYC
  • Gene Alias:
  • bHLHe39,c-Myc
  • Gene Description:
  • v-myc myelocytomatosis viral oncogene homolog (avian)
  • Gene Summary:
  • The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq
  • Other Designations:
  • avian myelocytomatosis viral oncogene homolog,myc proto-oncogene protein,v-myc avian myelocytomatosis viral oncogene homolog

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