Recombinant Human HCC-1/CCL14 重组人HCC-1/CCL14
产品名称： Recombinant Human HCC-1/CCL14 重组人HCC-1/CCL14
英文名称： Recombinant Human HCC-1/CCL14 重组人HCC-1/CCL14
产品编号： 90959ES05
产品价格： 415.00
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2025-02-07T09:08:27
使用范围： null
| 规格 | 价格 |
| 2 μg | 415.0 |
| 10 μg | 1045.0 |
| 50 μg | 2305.0 |
| 100 μg | 3675.0 |
- 联系人 : 李自转
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Human CCL14 is belonging to the CC chemokine family. It has two isoforms, CCL14a (HCC-1) and CCL14b (HCC-3). The sequence of HCC-3 differs from HCC-1 as follow: 27-27 R→ QTGGKPKVVKIQLKLVG. CCL14 was first isolated from the hemofiltrate of human patients with chronic renal failure. CCL14 promotes chemotaxis of T lymphocytes, monocytes and eosinophils, and inhibits infection of M-tropic human immunodeficiency virus type 1 and is a ligand for CCR1, CCR3 and CCR5. CCL14 is expressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations in plasma.
Product Properties
|
Synonyms |
CC-1 Protein, Human; CC-3 Protein, Human; CKB1 Protein, Human; FLJ16015 Protein, Human; HCC-1 Protein, Human; HCC-1(1-74) Protein, Human; HCC-1/HCC-3 Protein, Human; HCC-3 Protein, Human; MCIF Protein, Human; NCC-2 Protein, Human; NCC2 Protein, Human; SCYA14 Protein, Human; SCYL2 Protein, Human; SY14 Protein, Human |
|
Accession |
Q16627 |
|
GeneID |
6358 |
|
Source |
E.coli-derived human Hemofiltrate CC Chemokine-1 Protein, Thr22-Asn93 |
|
Molecular Weight |
Approximately 8.4 kDa. |
|
AA Sequence |
TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN |
|
Tag |
None |
|
Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
|
Purity |
> 96 % by SDS-PAGE and HPLC analyses. |
|
Biological Activity |
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-20 ng/ml. |
|
Endotoxin |
< 1.0 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl. |
|
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.
HB220425