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LRIG2抗体
产品名称: LRIG2抗体
英文名称: LRIG2
产品编号: bs-1845R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2025-02-07T10:24:52
使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1:100-500,IF=1:100-500,
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
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- 邮箱 : 3193328036@qq.com
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LRIG2 is produced in all human glioma cell lines and localizes to perinuclear compartments, cytoplasmic compartments and the cell surface. It acts as a negative feedback regulator of signaling through enhanced receptor ubiquitination and accelerated intracellular degradation. LRIG2 may function as a tumour suppressor since it downregulates the expression of EGF and the related proteins ErbB-2, ErbB-3 and ErbB-4, which all inhibit cancer cells from growth, migration and invasion.